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Desmocollin 1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q08554 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | CDHF1; DG2/DG3; DSC1; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 99987 Da |
| Dilution | WB 1:500~1:2000 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human Desmocollin 1 |
| Description | Desmocollin 1 is a component of intercellular desmosome junctions. It is involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | DSC1 |
|---|---|
| Synonyms | CDHF1 |
| Function | A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion (By similarity). Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation (By similarity). Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood (By similarity). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome {ECO:0000250|UniProtKB:P55849} |
| Tissue Location | Strongly expressed in epidermis, less in lymph node and tongue. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 195.00
$ 385.00
Cat# AP93160
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