COX16 Rabbit Polyclonal Antibody
COX16 Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC, IF |
|---|---|
| Primary Accession | Q9P0S2 |
| Reactivity | Human, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 12293 Da |
| Gene ID | 51241 |
|---|---|
| Other Names | Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial, hCOX16, COX16 |
| Dilution | IHC~~1:100~500 IF~~1:50~200 |
| Storage Conditions | -20℃ |
| Name | COX16 |
|---|---|
| Function | Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:29355485, PubMed:29381136, PubMed:33169484). Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2) (PubMed:29355485, PubMed:29381136). Interacts specifically with newly synthesized MT-CO2/COX and its copper center- forming metallochaperones SCO1, SCO2 and COA6 (PubMed:29381136). Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines (PubMed:29381136). |
| Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein |
| Tissue Location | Widely expressed. Expressed at higher level in skeletal muscle, heart and liver. |

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