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COX16 Rabbit Polyclonal Antibody

COX16 Rabbit Polyclonal Antibody

     
  • WB - COX16 Rabbit Polyclonal Antibody AP93363
    Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IHC, IF
Primary Accession Q9P0S2
Reactivity Human, Mouse
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 12293 Da
Additional Information
Gene ID 51241
Other Names Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial, hCOX16, COX16
Dilution IHC~~1:100~500
IF~~1:50~200
Storage Conditions-20℃
Protein Information
Name COX16
Function Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:29355485, PubMed:29381136, PubMed:33169484). Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2) (PubMed:29355485, PubMed:29381136). Interacts specifically with newly synthesized MT-CO2/COX and its copper center- forming metallochaperones SCO1, SCO2 and COA6 (PubMed:29381136). Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines (PubMed:29381136).
Cellular Location Mitochondrion inner membrane; Single-pass membrane protein
Tissue Location Widely expressed. Expressed at higher level in skeletal muscle, heart and liver.
Research Areas
Citations (0)
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$ 192.50
50% OFF
⚠️ Limit: 5 vials per order for discount.
Cat# AP93363
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