STB5L Rabbit Polyclonal Antibody
STB5L Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
---|---|
Primary Accession | Q9Y2K9 |
Reactivity | Human, Mouse |
Host | Polyclonal, Rabbit,IgG |
Clonality | Polyclonal |
Calculated MW | 131887 Da |
Gene ID | 9515 |
---|---|
Other Names | Syntaxin-binding protein 5-like, Lethal(2) giant larvae protein homolog 4, Tomosyn-2, STXBP5L, KIAA1006, LLGL4 |
Dilution | WB~~1:1000 |
Storage Conditions | -20℃ |
Name | STXBP5L |
---|---|
Synonyms | KIAA1006, LLGL4 |
Function | Plays a role in vesicle trafficking and exocytosis inhibition. In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating STX1A and STX4, key t-SNARE proteins involved in the fusion of insulin granules to the plasma membrane. Also plays a role in neurotransmitter release by inhibiting basal acetylcholine release from axon terminals and by preventing synaptic fatigue upon repetitive stimulation (By similarity). Promotes as well axonal outgrowth (PubMed:25504045). |
Cellular Location | Cytoplasm. Cell membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein Note=Cytoplasmic, and associated with vesicular membranes and the plasma membrane. |
Tissue Location | Detected in kidney, hippocampus and lung carcinoma. |

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