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STB5L Rabbit Polyclonal Antibody

STB5L Rabbit Polyclonal Antibody

     
  •  - STB5L Rabbit Polyclonal Antibody AP93479
    Western blot analysis of lysates from CACO2 cells, primary antibody was diluted at 1:1000, 4°over night
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9Y2K9
Reactivity Human, Mouse
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 131887 Da
Additional Information
Gene ID 9515
Other Names Syntaxin-binding protein 5-like, Lethal(2) giant larvae protein homolog 4, Tomosyn-2, STXBP5L, KIAA1006, LLGL4
Dilution WB~~1:1000
Storage Conditions-20℃
Protein Information
Name STXBP5L
Synonyms KIAA1006, LLGL4
Function Plays a role in vesicle trafficking and exocytosis inhibition. In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating STX1A and STX4, key t-SNARE proteins involved in the fusion of insulin granules to the plasma membrane. Also plays a role in neurotransmitter release by inhibiting basal acetylcholine release from axon terminals and by preventing synaptic fatigue upon repetitive stimulation (By similarity). Promotes as well axonal outgrowth (PubMed:25504045).
Cellular Location Cytoplasm. Cell membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein Note=Cytoplasmic, and associated with vesicular membranes and the plasma membrane.
Tissue Location Detected in kidney, hippocampus and lung carcinoma.
Citations (0)
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$ 385.00
Cat# AP93479
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