T150A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q86TG1 |
Other Accession | Q91WN2 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 28835 Da |
Antigen Region | 81-108 aa |
Gene ID | 129303 |
---|---|
Other Names | Transmembrane protein 150A, Transmembrane protein 150, TMEM150A, TMEM150 |
Target/Specificity | This T150A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the Central region of human T150A. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | T150A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TMEM150A |
---|---|
Synonyms | TMEM150 |
Function | Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K complex (PubMed:25608530). Acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (PubMed:25608530). May also play a role in fasting-induced catabolism (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein Note=Localizes mainly at the plasma membrane; only a minor fraction localizes on intracellular structures (PubMed:25608530) |
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Provided below are standard protocols that you may find useful for product applications.
Background
T150A is possible role in fasting-induced catabolism.
References
Zhang,J. Biochim. Biophys. Acta 1492 (1), 280-284 (2000)
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