|Application ||FC, IHC-P, WB, E|
|Calculated MW||145522 Da|
|Antigen Region||304-333 aa|
|Other Names||Centrosome and spindle pole-associated protein 1, CSPP1, CSPP|
|Target/Specificity||This CSPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the N-terminal region of human CSPP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CSPP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in cell-cycle-dependent microtubule organization.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Associated with mitotic spindles|
|Tissue Location||Expressed in adult and fetal brain with enrichment in the cerebellum. Detected in testis.|
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Provided below are standard protocols that you may find useful for product applications.
CSPP1 interacts with centrosomes and microtubules and plays a role in cell-cycle progression and spindle organization.
Asiedu, M., et al. Mol. Biol. Cell 20(5):1428-1440(2009) Patzke, S., et al. J. Cell. Physiol. 209(1):199-210(2006) Patzke, S., et al. Oncogene 24(7):1159-1173(2005)
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