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> home > Products > Secondary Antibodies > VDAC1 Recombinant Rabbit mAb, Mitochondrial Loading Control
VDAC1 Recombinant Rabbit mAb, Mitochondrial Loading Control
VDAC1 Recombinant Rabbit mAb, Mitochondrial Loading Control
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Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Recombinant |
| Calculated MW | 32 KDa |
| Physical State | Liquid |
| Immunogen | A synthesized peptide derived from human VDAC1 |
| Epitope Specificity | 1-66 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasm. Endosome membrane; Peripheral membrane protein (Probable). |
| SIMILARITY | Belongs to the VTA1 family. |
| SUBUNIT | Interacts with VPS4B. Interacts with CHMP1B. Interacts with CHMP2A; the interaction probably involves the open conformation of (polymerized) CHMP2A. May interact with CHMP3. Interacts with CHMP5; the interaction involves soluble CHMP5. Interacts with IST1. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Voltage dependent anion selective channel protein 1 (VDAC/Porin) belongs to the eukaryotic mitochondrial porin family and forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation selective. VDAC/Porin expression is observed in the heart,liver and skeletal muscle. |
| Dilution | WB=1:2000-10000,IHC-P=1:400-800,IHC-F=1:400-800,IF=1:100-500 |
|---|---|
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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$ 385.00
Cat# AP93983
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