Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
SERPINA9 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, FC, E |
|---|---|
| Primary Accession | Q86WD7 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46557 Da |
| Antigen Region | 194-222 aa |
| Gene ID | 327657 |
|---|---|
| Other Names | Serpin A9, Centerin, Germinal center B-cell-expressed transcript 1 protein, SERPINA9, GCET1, SERPINA11 |
| Target/Specificity | This SERPINA9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-222 amino acids from the Central region of human SERPINA9. |
| Dilution | IHC-P~~1:10~50 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SERPINA9 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SERPINA9 |
|---|---|
| Synonyms | GCET1, SERPINA11 |
| Function | Protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro). |
| Cellular Location | [Isoform 1]: Secreted. [Isoform 3]: Cytoplasm. [Isoform 5]: Cytoplasm. [Isoform 7]: Membrane; Single-pass type II membrane protein |
| Tissue Location | Highly expressed in normal germinal center (GC) B- cells and GC B-cell-derived malignancies. |
Provided below are standard protocols that you may find useful for product applications.
Background
SERPINA9 is a protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). This protein inhibits plasmin and thrombin with lower efficiency (in vitro).
References
Luke, M.M., et al. Stroke 40(2):363-368(2009) Paterson, M.A., et al. Am. J. Clin. Pathol. 130(1):117-126(2008) Montes-Moreno, S., et al. Blood 111(1):351-358(2008) Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008) Morrison, A.C., et al. Cerebrovasc. Dis. 26(4):420-424(2008)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
