LDHA Recombinant Rabbit mAb
LDHA Recombinant Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P, IHC-F, IF, FC, ICC, IP |
|---|---|
| Primary Accession | P00338 |
| Reactivity | Rat, Human, Mouse |
| Host | Rabbit |
| Clonality | Recombinant |
| Calculated MW | 37 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human LDHA |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the LDH/MDH superfamily. LDH family. |
| SUBUNIT | Homotetramer. |
| Post-translational modifications | ISGylated. |
| DISEASE | Glycogen storage disease 11 (GSD11) [MIM:612933]: A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue. Note=The disease is caused by mutations affecting the gene represented in this entry. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 3939 |
|---|---|
| Other Names | L-lactate dehydrogenase A chain, LDH-A, 1.1.1.27, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59, LDHA (HGNC:6535) |
| Target/Specificity | Metabolism of carbohydrates,Dehydrogenase Kits,NADP/NADPH,Carbohydrate metabolism,Energy Metabolism,Cancer,Energy Metabolism |
| Dilution | WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,ICC/IF=1:50-200,IF=1:50-200,IP=1:20-50,Flow-Cyt=1:20-50 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | LDHA (HGNC:6535) |
|---|---|
| Function | Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Predominantly expressed in anaerobic tissues such as skeletal muscle and liver. |

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Background
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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