- CITATIONS: 1
|Application ||IHC-P, WB, E|
|Other Accession||Q45R42, Q99PH1|
|Calculated MW||72717 Da|
|Antigen Region||531-559 aa|
|Other Names||Leucine-rich repeat-containing protein 4, Brain tumor-associated protein BAG, Nasopharyngeal carcinoma-associated gene 14 protein, Netrin-G2 ligand, NGL-2, LRRC4, BAG|
|Target/Specificity||This LRRC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the C-terminal region of human LRRC4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRRC4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity).|
|Cellular Location||Membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane Note=LRRC4 and DLG4 are interdependent for synaptic localization|
|Tissue Location||Specifically expressed in brain.|
Provided below are standard protocols that you may find useful for product applications.
The exact function of LRRC4 is unknown.
Wu, M., et al. J. Cell. Physiol. 214(1):65-74(2008)
Zhang, Z., et al. BMC Mol. Biol. 9, 99 (2008) :
Wu, M., et al. J. Neurooncol. 80(2):133-142(2006)
Wu, M., et al. Mol. Biol. Cell 17(8):3534-3542(2006)
Zhang, Q.H., et al. Acta Biochim. Biophys. Sin. (Shanghai) 37(10):680-687(2005)
Zhang, Q.H., et al. Acta Biochim. Biophys. Sin. (Shanghai) 37(8):532-540(2005)
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