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NXPH1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | P58417 |
| Other Accession | Q63366, Q61200, Q5E9M6 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 31082 Da |
| Antigen Region | 56-85 aa |
| Gene ID | 30010 |
|---|---|
| Other Names | Neurexophilin-1, NXPH1, NPH1 |
| Target/Specificity | This NXPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human NXPH1. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NXPH1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NXPH1 |
|---|---|
| Synonyms | NPH1 |
| Function | May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
NXPH1 is a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons.
References
?Xu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(5):2136-2140(2010)
?Shen, L., et al. Neuroimage (2010) In press :
?van den Oord, E.J., et al. Arch. Gen. Psychiatry 65(9):1062-1071(2008)
?Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :
?Ohira, M., et al. Cancer Lett. 197 (1-2), 63-68 (2003) :
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