|Application ||FC, IHC-P, WB, E|
|Other Accession||Q63366, Q61200, Q5E9M6|
|Calculated MW||31082 Da|
|Antigen Region||56-85 aa|
|Other Names||Neurexophilin-1, NXPH1, NPH1|
|Target/Specificity||This NXPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human NXPH1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NXPH1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.|
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Provided below are standard protocols that you may find useful for product applications.
NXPH1 is a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons.
?Xu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(5):2136-2140(2010)
?Shen, L., et al. Neuroimage (2010) In press :
?van den Oord, E.J., et al. Arch. Gen. Psychiatry 65(9):1062-1071(2008)
?Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :
?Ohira, M., et al. Cancer Lett. 197 (1-2), 63-68 (2003) :
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