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ABHEB Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q96IU4 |
| Other Accession | A7YY28 |
| Reactivity | Human |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 22346 Da |
| Antigen Region | 150-179 aa |
| Gene ID | 84836 |
|---|---|
| Other Names | Alpha/beta hydrolase domain-containing protein 14B, Abhydrolase domain-containing protein 14B, 3---, CCG1-interacting factor B, ABHD14B, CIB |
| Target/Specificity | This ABHEB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the C-terminal region of human ABHEB. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ABHEB Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ABHD14B {ECO:0000303|PubMed:31478652, ECO:0000312|HGNC:HGNC:28235} |
|---|---|
| Function | Acts as an atypical protein-lysine deacetylase in vitro (PubMed:31478652). Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein- lysine residues (PubMed:31478652). Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo (Probable). Has hydrolase activity towards various surrogate p- nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate (PubMed:31478652, PubMed:14672934). May activate transcription (PubMed:14672934). |
| Cellular Location | Cytoplasm. Nucleus. Note=Predominantly cytoplasmic |
| Tissue Location | Ubiquitous (PubMed:14672934). Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, placenta, lung, liver, skeletal muscle, pancreas and kidney (PubMed:14672934). |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
ABHEB has hydrolase activity towards p-nitrophenyl butyrate (in vitro). It may activate transcription.
References
Padmanabhan, B., et al. Acta Crystallogr. D Biol. Crystallogr. 56 (PT 11), 1479-1481 (2000)
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$ 365.00
$ 140.00
Cat# AP9700b
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