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M11D1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - M11D1 Antibody  (N-term) AP9974a
    Western blot analysis of M11D1 Antibody (N-term) (Cat. #AP9974a) in HL-60 cell line lysates (35ug/lane). M11D1 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - M11D1 Antibody  (N-term) AP9974a
    M11D1 Antibody (N-term) (Cat. #AP9974a) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the M11D1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • FC - M11D1 Antibody  (N-term) AP9974a
    M11D1 Antibody (N-term) (Cat. #AP9974a) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, WB, IHC-P, E
Primary Accession Q9H7H0
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 50734 Da
Antigen Region 88-116 aa
Additional Information
Gene ID 64745
Other Names Methyltransferase-like protein 17, mitochondrial, 211-, False p73 target gene protein, Methyltransferase 11 domain-containing protein 1, Protein RSM22 homolog, mitochondrial, METTL17, METT11D1
Target/Specificity This M11D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the N-terminal region of human M11D1.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsM11D1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name METTL17
Synonyms METT11D1 {ECO:0000303|PubMed:24137763}
Function Probable S-adenosyl-L-methionine-dependent RNA methyltransferase required to stabilize the mitochondrial small ribosomal subunit (mt-SSU). Required for protein translation in mitochondria.
Cellular Location Mitochondrion matrix {ECO:0000250|UniProtKB:Q3U2U7}
Research Areas
Citations (0)
citation

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Background

M11D1 may be a component of the mitochondrial small ribosomal subunit.

References

Lim, J., et al. Cell 125(4):801-814(2006)
Saveanu, C., et al. J. Biol. Chem. 276(19):15861-15867(2001)

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$ 365.00
$ 140.00
Cat# AP9974a
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