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> home > Products > Primary Antibodies > Antibody Collections > Recombinant Antibodies > Anti-SLC2A8 Reference Antibody (VB1-050)
Anti-SLC2A8 Reference Antibody (VB1-050)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | Q9NY64 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Calculated MW | 150 KDa |
| Target/Specificity | SLC2A8 |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Storage | -80°C for 2 years under sterile conditions； -20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles. |
| Name | SLC2A8 (HGNC:13812) |
|---|---|
| Function | Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose (By similarity). Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1 (PubMed:27922102). Also able to mediate the transport of dehydroascorbate. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9JJZ1}; Multi-pass membrane protein. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9JJZ1}; Multi-pass membrane protein. Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration {ECO:0000250|UniProtKB:Q9JJZ1} |
| Tissue Location | Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 365.00
Cat# APR10293
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