Anti-P-Selectin / CD62p Reference Antibody (crizanlizumab)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, E, FTA |
---|---|
Primary Accession | P49908 |
Reactivity | Cynomolgus, Human, Mouse |
Clonality | Monoclonal |
Isotype | IgG2SA |
Calculated MW | 145 KDa |
Target/Specificity | P-Selectin / CD62p |
---|---|
Endotoxin | < 0.001EU/ µg,determined by LAL method. |
Conjugation | Unconjugated |
Expression system | CHO Cell |
Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
Storage | -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles. |
Name | SELENOP {ECO:0000303|PubMed:27645994, ECO:0000312|HGNC:HGNC:10751} |
---|---|
Function | Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis. |
Cellular Location | Secreted. Note=Passes from plasma into the glomerular filtrate where it is removed by endocytosis mediated by LRP2 in the proximal tubule epithelium. {ECO:0000250|UniProtKB:P70274} |
Tissue Location | Made in the liver and heart and secreted into the plasma. It is also found in the kidney |
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