CCDC69 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
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Primary Accession | A6NI79 |
Other Accession | NP_056436, 45935391 |
Reactivity | Human, Mouse, Rat |
Host | Chicken |
Clonality | Polyclonal |
Isotype | IgY |
Calculated MW | 34796 Da |
Application Notes | CCDC69 antibody can be used for detection of CCDC69 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL. |
Gene ID | 26112 |
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Target/Specificity | CCDC69; |
Reconstitution & Storage | CCDC69 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Precautions | CCDC69 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCDC69 (HGNC:24487) |
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Function | May act as a scaffold to regulate the recruitment and assembly of spindle midzone components. Required for the localization of AURKB and PLK1 to the spindle midzone. |
Cellular Location | Cytoplasm, cytoskeleton, spindle. Midbody Note=During early anaphase, localizes along overlapping interpolar microtubules between the separating chromosomes. During late anaphase, localizes to the center of spindle midzone. Concentrated at the midbody during telophase. |
Tissue Location | Highly expressed in duodenum, esophagus, pancreas, prostate, salivary gland, thymus and urinary bladder |
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Provided below are standard protocols that you may find useful for product applications.
Background
CCDC69 Antibody: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. The CCDC47 gene maps to chromosome 5 at 5q33.1. Little is known about this protein.
References
Steinmetz MO, Jelesarov I, Matousek WM, et al. Molecular basis of coiled-coil formation. Proc. Natl. Acad. Sci. USA2007; 104:7062-7.
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