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YPEL1 Antibody

     
  • WB - YPEL1 Antibody ASC11456
    Western blot analysis of YPEL1 in Hela cell lysate with YPEL1 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
    detail
  • ICC - YPEL1 Antibody ASC11456
    Immunocytochemistry of YPEL1 in HeLa cells with YPEL1 antibody at 2.5 µg/mL.
    detail
  • IF - YPEL1 Antibody ASC11456
    Immunofluorescence of YPEL1 in HeLa cells with YPEL1 antibody at 20 µg/mL.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, ICC, E
Primary Accession O60688
Other Accession NP_037445, 9558721
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 13575 Da
Application Notes YPEL1 antibody can be used for detection of YPEL1 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 µg/mL. For immunofluorescence start at 2.5 µg/mL.
Additional Information
Gene ID 29799
Target/Specificity YPEL1;
Reconstitution & Storage YPEL1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsYPEL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name YPEL1
Function May play a role in epithelioid conversion of fibroblasts.
Cellular Location Nucleus.
Citations (0)
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Background

YPEL1 Antibody: YPEL1 (yippee-like 1) is thought to play a role in the epitheloid conversion of fibroblasts and the regulation of the cellular morphology. It is a 119 amino acid protein that localizes to the nucleus and belongs to a family of yippee-like proteins that include YPEL2 - 5, all of which localize to the centrosome and nucleus and are widely expressed in both adult and fetal tissue. The family of human YPEL proteins share a high degree of sequence homology with their rodent homologs, suggesting a conserved function between species. YPEL1 might be an important factor during the development and malignant transformation of tissues.

References

Farlie P, Reid C, Wilcox S, et al. YPEL1: a novel nuclear protein that induces an epithelial-like morphology in fibroblasts. Genes Cells 2001; 6:619-29.
Hosono K, Sasaki T, Minoshima S, et al. Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. Gene 2004; 340: 31-43
Abiatari I, Kiladze M, Kerkadze V, et al. Expression of YPEL1 in pancreatic cancer cell lines and tissues. Georgian Med. News 2009; (175):60-2.

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$ 379.00
Cat# ASC11456
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