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CPB1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant CPB1.

     
  • IP - CPB1 Antibody (monoclonal) (M01) AT1605a
    Immunoprecipitation of CPB1 transfected lysate using anti-CPB1 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with CPB1 MaxPab rabbit polyclonal antibody.
    detail
  • WB - CPB1 Antibody (monoclonal) (M01) AT1605a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (70.18 KDa) .
    detail
  • WB - CPB1 Antibody (monoclonal) (M01) AT1605a
    Western Blot analysis of CPB1 expression in transfected 293T cell line by CPB1 monoclonal antibody (M01), clone 4D5.

    Lane 1: CPB1 transfected lysate(47.4 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • IHC - CPB1 Antibody (monoclonal) (M01) AT1605a
    Immunoperoxidase of monoclonal antibody to CPB1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IP
Primary Accession P15086
Other Accession BC015338
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4D5
Calculated MW 47368 Da
Additional Information
Gene ID 1360
Other Names Carboxypeptidase B, Pancreas-specific protein, PASP, CPB1, CPB, PCPB
Target/Specificity CPB1 (AAH15338, 14 a.a. ~ 417 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCPB1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma.

References

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.The NMR structure and dynamics of the two-domain tick carboxypeptidase inhibitor reveal flexibility in its free form and stiffness upon binding to human carboxypeptidase B. Pantoja-Uceda D, et al. Biochemistry, 2008 Jul 8. PMID 18558717.TAFI and pancreatic carboxypeptidase B modulate in vitro capillary tube formation by human microvascular endothelial cells. Guimar?es AH, et al. Arterioscler Thromb Vasc Biol, 2007 Oct. PMID 17673703.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.

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$ 350.00
Cat# AT1605a
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Availability: 7-10 days
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