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CRX Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant CRX.

     
  • WB - CRX Antibody (monoclonal) (M03) AT1638a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.19 KDa) .
    detail
  • WB - CRX Antibody (monoclonal) (M03) AT1638a
    CRX monoclonal antibody (M03), clone 2F12 Western Blot analysis of CRX expression in PC-12 ( (Cat # AT1638a )
    detail
  • E - CRX Antibody (monoclonal) (M03) AT1638a
    Detection limit for recombinant GST tagged CRX is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O43186
Other Accession NM_000554
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2F12
Calculated MW 32261 Da
Additional Information
Gene ID 1406
Other Names Cone-rod homeobox protein, CRX, CORD2
Target/Specificity CRX (NP_000545, 1 a.a. ~ 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCRX Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

References

1.OTX2 and CRX rescue overlapping and photoreceptor-specific functions in the Drosophila eye.Terrell D, Xie B, Workman M, Mahato S, Zelhof A, Gebelein B, Cook T.Dev Dyn. 2012 Jan;241(1):215-28. doi: 10.1002/dvdy.22782. Epub 2011 Nov 23.

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$ 350.00
Cat# AT1638a
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