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DNAJA2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant DNAJA2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | O60884 |
| Other Accession | BC013044 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 2A11-F2 |
| Calculated MW | 45746 Da |
| Gene ID | 10294 |
|---|---|
| Other Names | DnaJ homolog subfamily A member 2, Cell cycle progression restoration gene 3 protein, Dnj3, Dj3, HIRA-interacting protein 4, Renal carcinoma antigen NY-REN-14, DNAJA2, CPR3, HIRIP4 |
| Target/Specificity | DNAJA2 (AAH13044, 1 a.a. ~ 412 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DNAJA2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro.
References
1.Cell line specific modulation of extracellular a?](42) by hsp40.Carnini A, Scott LO, Ahrendt E, Proft J, Winkfein RJ, Kim SW, Colicos MA, Braun JE.PLoS One. 2012;7(5):e37755. Epub 2012 May 29.2.Quercetin targets cysteine string protein (CSPalpha) and impairs synaptic transmission.Xu F, Proft J, Gibbs S, Winkfein B, Johnson JN, Syed N, Braun JE.PLoS One. 2010 Jun 10;5(6):e11045.3.RDJ2 (DNAJA2) chaperones neural G protein signaling pathways.Rosales-Hernandez A, Beck KE, Zhao X, Braun AP, Braun JE.Cell Stress Chaperones. 2009 Jan;14(1):71-82. Epub 2008 Jul 2.
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