EMD Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant EMD.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF, E |
---|---|
Primary Accession | P50402 |
Other Accession | BC000738 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG2a Kappa |
Clone Names | 3B9 |
Calculated MW | 28994 Da |
Gene ID | 2010 |
---|---|
Other Names | Emerin, EMD, EDMD, STA |
Target/Specificity | EMD (AAH00738, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | EMD Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
References
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.A novel custom resequencing array for dilated cardiomyopathy. Zimmerman RS, et al. Genet Med, 2010 May. PMID 20474083.Emery-Dreifuss dystrophy: a 4-year follow-up on a laminopathy of special interest. Hausmanowa-Petrusewicz I, et al. Neurol Neurochir Pol, 2009 Sep-Oct. PMID 20054742.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases. Tifft KE, et al. J Cell Sci, 2009 Oct 15. PMID 19789182.
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