GNG2 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a full length recombinant GNG2.
|Calculated MW||7850 Da|
|Other Names||Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, G gamma-I, GNG2|
|Target/Specificity||GNG2 (AAH20774, 1 a.a. ~ 71 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||GNG2 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Heterotrimeric G proteins play vital roles in cellular responses to external signals. The specificity of a G protein-receptor interaction is primarily mediated by the gamma subunit.
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Differential regulation of phospholipase C-beta2 activity and membrane interaction by Galphaq, Gbeta1gamma2, and Rac2. Gutman O, et al. J Biol Chem, 2010 Feb 5. PMID 20007712.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Dissociation of heterotrimeric g proteins in cells. Lambert NA. Sci Signal, 2008 Jun 24. PMID 18577758.Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. Luttrell LM. Mol Biotechnol, 2008 Jul. PMID 18240029.
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