HCLS1 Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a partial recombinant HCLS1.
|Application ||WB, IHC, IF, E|
|Calculated MW||54014 Da|
|Other Names||Hematopoietic lineage cell-specific protein, Hematopoietic cell-specific LYN substrate 1, LckBP1, p75, HCLS1, HS1|
|Target/Specificity||HCLS1 (AAH16758, 266 a.a. ~ 355 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||HCLS1 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
HS1 complexes with cytoskeleton adapters in normal and malignant chronic lymphocytic leukemia B cells. Muzio M, et al. Leukemia, 2007 Sep. PMID 17508001.A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Lim J, et al. Cell, 2006 May 19. PMID 16713569.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.The coiled-coil domain is required for HS1 to bind to F-actin and activate Arp2/3 complex. Hao JJ, et al. J Biol Chem, 2005 Nov 11. PMID 16157603.Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. Tao WA, et al. Nat Methods, 2005 Aug. PMID 16094384.
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