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NR1H4 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant NR1H4.

     
  • IF - NR1H4 Antibody (monoclonal) (M01) AT3098a
    Immunofluorescence of monoclonal antibody to NR1H4 on HepG2 cell. [antibody concentration 10 ug/ml]
    detail
  • WB - NR1H4 Antibody (monoclonal) (M01) AT3098a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
    detail
  • WB - NR1H4 Antibody (monoclonal) (M01) AT3098a
    NR1H4 monoclonal antibody (M01), clone 1G11 Western Blot analysis of NR1H4 expression in HepG2 ( (Cat # AT3098a )
    detail
  • WB - NR1H4 Antibody (monoclonal) (M01) AT3098a
    NR1H4 monoclonal antibody (M01), clone 1G11. Western Blot analysis of NR1H4 expression in A-431 ( (Cat # AT3098a )
    detail
  • E - NR1H4 Antibody (monoclonal) (M01) AT3098a
    Detection limit for recombinant GST tagged NR1H4 is 1 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession Q96RI1
Other Accession NM_005123
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1G11
Calculated MW 55914 Da
Additional Information
Gene ID 9971
Other Names Bile acid receptor, Farnesoid X-activated receptor, Farnesol receptor HRR-1, Nuclear receptor subfamily 1 group H member 4, Retinoid X receptor-interacting protein 14, RXR-interacting protein 14, NR1H4, BAR, FXR, HRR1, RIP14
Target/Specificity NR1H4 (NP_005114, 363 a.a. ~ 472 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsNR1H4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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References

The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity. Popescu IR, et al. FEBS Lett, 2010 Jul 2. PMID 20447400.Bile acids and their nuclear receptor FXR: Relevance for hepatobiliary and gastrointestinal disease. Gadaleta RM, et al. Biochim Biophys Acta, 2010 Jul. PMID 20399894.Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. Roberts KE, et al. Gastroenterology, 2010 Jul. PMID 20346360.Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids. Erichsen TJ, et al. J Hepatol, 2010 Apr. PMID 20189675.Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells. Catalano S, et al. J Biol Chem, 2010 Feb 19. PMID 20026603.

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$ 350.00
Cat# AT3098a
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