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TCF3 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant TCF3.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P15923 |
| Other Accession | NM_003200 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 5G2 |
| Calculated MW | 67600 Da |
| Gene ID | 6929 |
|---|---|
| Other Names | Transcription factor E2-alpha, Class B basic helix-loop-helix protein 21, bHLHb21, Immunoglobulin enhancer-binding factor E12/E47, Immunoglobulin transcription factor 1, Kappa-E2-binding factor, Transcription factor 3, TCF-3, Transcription factor ITF-1, TCF3, BHLHB21, E2A, ITF1 |
| Target/Specificity | TCF3 (NP_003191, 545 a.a. ~ 654 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | TCF3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The TCF3 gene, also called E2A, encodes 2 basic helix-loop-helix (bHLH) transcription factors, E12 and E47, through alternative splicing. E12 and E47 are involved in regulation of immunoglobulin gene expression (Bain et al., 1994 [PubMed 8001125]).
References
1.Synaptic Cross-talk between N-Methyl-D-aspartate Receptors and LAPSER1-{beta}-Catenin at Excitatory Synapses.Schmeisser MJ, Grabrucker AM, Bockmann J, Boeckers TM.J Biol Chem. 2009 Oct 16;284(42):29146-57. Epub 2009 Aug 24.
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