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EHD4 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9H223 |
| Other Accession | Q9EQP2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | polyclonal |
| Calculated MW | H=61;M=61 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 30844 |
|---|---|
| Antigen Region | 527-561 aa |
| Other Names | EH domain-containing protein 4, Hepatocellular carcinoma-associated protein 10/11, PAST homolog 4, EHD4, HCA10, HCA11, PAST4 |
| Dilution | WB~~1:1000 |
| Target/Specificity | This EHD4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 527-561 amino acids from the C-terminal region of human EHD4. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | EHD4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EHD4 (HGNC:3245) |
|---|---|
| Function | ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in early endosomal transport (PubMed:17233914, PubMed:18331452). During sprouting angiogenesis, in complex with PACSIN2 and MICALL1, forms recycling endosome-like tubular structure at asymmetric adherens junctions to control CDH5 trafficking (By similarity). |
| Cellular Location | Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane {ECO:0000250|UniProtKB:Q9EQP2}; Peripheral membrane protein; Cytoplasmic side. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q9EQP2} |
| Tissue Location | Highly expressed in pancreas and heart. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role in early endosomal transport.
References
Wang Y.,et al.J. Immunol. 169:1102-1109(2002).
Wang Y.-G.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Benjamin S.,et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
Pohl U.,et al.Genomics 63:255-262(2000).
Rush J.,et al.Nat. Biotechnol. 23:94-101(2005).
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