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TCL1A Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB |
|---|---|
| Primary Accession | P56279 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=13 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 8115 |
|---|---|
| Antigen Region | 32-66 aa |
| Other Names | T-cell leukemia/lymphoma protein 1A, Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1, TCL1A, TCL1 |
| Dilution | FC~~1:25 WB~~1:1000 |
| Target/Specificity | This TCL1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the Central region of human TCL1A. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TCL1A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TCL1A |
|---|---|
| Synonyms | TCL1 |
| Function | Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. |
| Cellular Location | Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum. Note=Microsomal fraction |
| Tissue Location | Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
References
Virgilio L.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:12530-12534(1994).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Fu T.-B.,et al.Cancer Res. 54:6297-6301(1994).
Laine J.,et al.Mol. Cell 6:395-407(2000).
Pekarsky Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:3028-3033(2000).
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