(DANRE) ada Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q6DG22 |
| Reactivity | Zebrafish |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Clone/Animal Names | RB47223 |
| Calculated MW | 40844 Da |
| Antigen Region | 114-148 aa |
| Gene ID | 436919 |
|---|---|
| Other Names | Adenosine deaminase, Adenosine aminohydrolase, ada |
| Target/Specificity | This (DANRE) ada antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 114-148 amino acids of DANRE ADA. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | (DANRE) ada Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ada |
|---|---|
| Function | Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P00813}; Peripheral membrane protein; Extracellular side. Cell junction {ECO:0000250|UniProtKB:P00813} Cytoplasmic vesicle lumen {ECO:0000250|UniProtKB:P03958}. Cytoplasm. Lysosome {ECO:0000250|UniProtKB:P00813} |

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Background
Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity).
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