AEBP1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8IUX7 |
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Other Accession | NP_001120.3 |
Clone Names | 80305116 |
Gene ID | 165 |
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Other Names | Adipocyte enhancer-binding protein 1, AE-binding protein 1, Aortic carboxypeptidase-like protein, AEBP1, ACLP |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | AEBP1 |
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Synonyms | ACLP |
Function | [Isoform 1]: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix. |
Cellular Location | [Isoform 1]: Secreted {ECO:0000250|UniProtKB:Q640N1} |
Tissue Location | Expressed in osteoblast and visceral fat. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The adipocyte enhancer binding protein 1 is atranscriptional repressor with carboxypeptidase (CP) activity. Thisprotein binds to a regulatory sequence, adipocyte enhancer 1(AE-1), located in the proximal promoter region of the adipose P2(aP2) gene, which encodes the adipocyte fatty-acid binding protein.It is characterized as a member of the regulatory B-like CP family.This protein seems to be activated by a novel mechanism, wherebythe direct binding of DNA enhances its protease activity.Adipocyte-enhancer binding protein 1 may play a role indifferentiated vascular smooth muscle cells.
References
Majdalawieh, A., et al. Nucl Recept Signal 8, E004 (2010) :Schissel, S.L., et al. Am. J. Pathol. 174(3):818-828(2009)Zhang, L., et al. Mol. Med. 11 (1-12), 39-47 (2005) :Layne, M.D., et al. Mol. Cell. Biol. 21(15):5256-5261(2001)Muise, A.M., et al. Biochem. J. 343 PT 2, 341-345 (1999) :
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