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DNAJB8 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8NHS0 |
|---|---|
| Other Accession | NP_699161.1 |
| Clone Names | 100120125 |
| Gene ID | 165721 |
|---|---|
| Other Names | DnaJ homolog subfamily B member 8, DNAJB8 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DNAJB8 |
|---|---|
| Function | Efficient suppressor of aggregation and toxicity of disease- associated polyglutamine proteins. |
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Provided below are standard protocols that you may find useful for product applications.
Background
DNAJB8 belongs to the evolutionarily conserved DNAJ/HSP40family of proteins, which regulate molecular chaperone activity bystimulating ATPase activity. DNAJ proteins may have up to 3distinct domains: a conserved 70-amino acid J domain, usually atthe N terminus; a glycine/phenylalanine (G/F)-rich region; and acysteine-rich domain containing 4 motifs resembling a zinc fingerdomain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied byOMIM].
References
Hageman, J., et al. Mol. Cell 37(3):355-369(2010)Lamesch, P., et al. Genomics 89(3):307-315(2007)Ohtsuka, K., et al. Cell Stress Chaperones 5(2):98-112(2000)
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