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GEM Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P55040 |
|---|---|
| Clone Names | 81020115 |
| Gene ID | 2669 |
|---|---|
| Other Names | GTP-binding protein GEM, GTP-binding mitogen-induced T-cell protein, RAS-like protein KIR, GEM, KIR |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GEM |
|---|---|
| Synonyms | KIR |
| Function | Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. |
| Cellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side |
| Tissue Location | Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the RAD/GEMfamily of GTP-binding proteins. It is associated with the innerface of the plasma membrane and could play a role as a regulatoryprotein in receptor-mediated signal transduction. Alternativesplicing occurs at this locus and two transcript variants encodingthe same protein have been identified.
References
Wang, A., et al. J. Bacteriol. 192(11):2809-2815(2010)Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Splingard, A., et al. J. Biol. Chem. 282(3):1905-1915(2007)Opatowsky, Y., et al. FEBS Lett. 580(25):5959-5964(2006)Kelly, K. Trends Cell Biol. 15(12):640-643(2005)
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