LDLRAD3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q86YD5 |
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Clone Names | 100126180 |
Gene ID | 143458 |
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Other Names | Low-density lipoprotein receptor class A domain-containing protein 3, LDLRAD3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | LDLRAD3 (HGNC:27046) |
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Synonyms | LRAD3 |
Function | May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. May regulate ITCH and NEDD4 E3 ligase activity and degradation (PubMed:26854353). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed at high levels in brain, lung, skeletal muscle, and pancreas. Expressed at moderate levels in heart, placenta, and kidney but not detected in the liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
The specific function of the protein remains unknown.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Kantojarvi, K., et al. Psychiatr. Genet. 20(3):102-108(2010)
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