GALNS Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P34059 |
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Clone Names | 101008224 |
Gene ID | 2588 |
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Other Names | N-acetylgalactosamine-6-sulfatase, Chondroitinsulfatase, Chondroitinase, Galactose-6-sulfate sulfatase, GalN6S, N-acetylgalactosamine-6-sulfate sulfatase, GalNAc6S sulfatase, GALNS |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GALNS |
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Cellular Location | Lysosome. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes N-acetylgalactosamine-6-sulfatase whichis a lysosomal exohydrolase required for the degradation of theglycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate.Sequence alterations including point, missense and nonsensemutations, as well as those that affect splicing, result in adeficiency of this enzyme. Deficiencies of this enzyme lead toMorquio A syndrome, a lysosomal storage disorder. [provided byRefSeq].
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Bank, R.A., et al. Mol. Genet. Metab. 97(3):196-201(2009)Yan, S., et al. Biopolymers 92(5):399-404(2009)Carraresi, L., et al. Clin. Chim. Acta 397 (1-2), 72-76 (2008) :Bhattacharyya, S., et al. J. Biol. Chem. 283(15):9523-9530(2008)
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