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SLC44A1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8WWI5 |
|---|---|
| Clone Names | 100507053 |
| Gene ID | 23446 |
|---|---|
| Other Names | Choline transporter-like protein 1, CDw92, Solute carrier family 44 member 1, CD92, SLC44A1, CD92, CDW92, CTL1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP14061c was selected from the Center region of SLC44A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC44A1 (HGNC:18798) |
|---|---|
| Synonyms | CD92, CDW92, CTL1 |
| Function | Choline/H+ antiporter (PubMed:19357133, PubMed:23651124, PubMed:31855247, PubMed:33789160). Also acts as a high-affinity ethanolamine/H+ antiporter, regulating the supply of extracellular ethanolamine (Etn) for the CDP-Etn pathway, redistribute intracellular Etn and balance the CDP-Cho and CDP-Etn arms of the Kennedy pathway (PubMed:33789160). Involved in membrane synthesis and myelin production (PubMed:31855247). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in various cells of the hematopoietic system. |
Provided below are standard protocols that you may find useful for product applications.
Background
SLC44A1 is a choline transporter. May be involved in membrane synthesis and myelin production.
References
Nakamura, T., et al. Biol. Pharm. Bull. 33(4):691-696(2010)Machova, E., et al. J. Neurochem. 110(4):1297-1309(2009)Michel, V., et al. FASEB J. 23(8):2749-2758(2009)Perry, J.R., et al. Nat. Genet. 41(6):648-650(2009)Yuan, Z., et al. Physiol. Genomics 26(1):76-90(2006)
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