PRPF31 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8WWY3 |
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Clone Names | 100525180 |
Gene ID | 26121 |
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Other Names | U4/U6 small nuclear ribonucleoprotein Prp31, Pre-mRNA-processing factor 31, Serologically defined breast cancer antigen NY-BR-99, U4/U6 snRNP 61 kDa protein, Protein 61K, hPrp31, PRPF31, PRP31 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PRPF31 |
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Synonyms | PRP31 |
Function | Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11867543, PubMed:28781166). Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:11867543). |
Cellular Location | Nucleus. Nucleus speckle. Nucleus, Cajal body. Note=Predominantly found in speckles and in Cajal bodies. |
Tissue Location | Ubiquitously expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a component of the spliceosome complexand is one of several retinitis pigmentosa-causing genes. When thegene product is added to the spliceosome complex, activationoccurs.
References
Schneider, M., et al. Nat. Struct. Mol. Biol. 17(2):216-221(2010)Bujakowska, K., et al. Invest. Ophthalmol. Vis. Sci. 50(12):5927-5933(2009)Potkin, S.G., et al. PLoS ONE 4 (8), E6501 (2009) :Liu, S., et al. Science 316(5821):115-120(2007)Sullivan, L.S., et al. Invest. Ophthalmol. Vis. Sci. 47(10):4579-4588(2006)
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