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SERINC3 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q13530 |
|---|---|
| Clone Names | 110617080 |
| Gene ID | 10955 |
|---|---|
| Other Names | Serine incorporator 3, Tumor differentially expressed protein 1, SERINC3, DIFF33, TDE1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SERINC3 |
|---|---|
| Synonyms | DIFF33, TDE1 {ECO:0000303|PubMed:1055979 |
| Function | Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q86VE9}; Multi-pass membrane protein. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9QZI9}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9QZI9} |
| Tissue Location | Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
SERINC3 may be involved in cellular transformation.
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Bossolasco, M., et al. Oncogene 25(33):4549-4558(2006)Deloukas, P., et al. Nature 414(6866):865-871(2001)Bossolasco, M., et al. Mol. Carcinog. 26(3):189-200(1999)Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995) :
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