ROD1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O95758 |
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Clone Names | 110808052 |
Gene ID | 9991 |
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Other Names | Polypyrimidine tract-binding protein 3, Regulator of differentiation 1, Rod1, PTBP3, ROD1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PTBP3 |
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Synonyms | ROD1 |
Function | RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U). |
Tissue Location | Expressed in several hematopoietic cell lines examined. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ROD1 is a functional homolog of nrd1, an S. pombeRNA-binding protein that suppresses the onset ofdifferentiation.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :Sadvakassova, G., et al. J. Cell. Physiol. 220(3):672-679(2009)Yamamoto, H., et al. Mol. Cell. Biol. 19(5):3829-3841(1999)
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