GANC Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8TET4 |
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Clone Names | 100311199 |
Gene ID | 2595 |
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Other Names | Neutral alpha-glucosidase C, GANC |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GANC |
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Function | Has alpha-glucosidase activity. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Glycosyl hydrolase enzymes hydrolyse the glycosidic bondbetween two or more carbohydrates, or between a carbohydrate and anon-carbohydrate moiety. This gene encodes a member of glycosylhydrolases family 31. This enzyme hydrolyses terminal, non-reducing1,4-linked alpha-D-glucose residues and releases alpha-D-glucose.This is a key enzyme in glycogen metabolism and its gene localizesto a chromosomal region (15q15) that is associated withsusceptibility to diabetes.
References
Oba-Shinjo, S.M., et al. J. Neurol. 256(11):1881-1890(2009)Kawabata, Y., et al. FEBS Lett. 555(3):623-630(2003)Dgany, O., et al. Am. J. Hum. Genet. 71(6):1467-1474(2002)Hirschhorn, R., et al. Proc. Natl. Acad. Sci. U.S.A. 99(21):13642-13646(2002)Usuki, F., et al. Muscle Nerve 11(4):365-371(1988)
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