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DRG2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P55039
Clone Names 110826107
Additional Information
Gene ID 1819
Other Names Developmentally-regulated GTP-binding protein 2, DRG-2, DRG2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DRG2 {ECO:0000303|PubMed:29915238, ECO:0000312|HGNC:HGNC:3030}
Function Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.
Cellular Location Nucleus. Cytoplasm
Tissue Location Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes
Research Areas
Citations (0)

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Background

The DRG2 gene encodes the developmentally regulatedGTP-binding protein 2, a name derived from the fact that it sharessignificant similarity to known GTP-binding proteins. DRG2 wasidentified because it is expressed in normal fibroblasts but not inSV40-transformed fibroblasts. Read-through transcripts containingthis gene and a downstream gene have been identified, but they arenot thought to encode a fusion protein. This gene is located withinthe Smith-Magenis syndrome region on chromosome 17. [provided byRefSeq].

References

Song, H., et al. J. Biochem. 135(3):331-335(2004)Bi, W., et al. Genome Res. 12(5):713-728(2002)Li, B., et al. Biochim. Biophys. Acta 1491 (1-3), 196-204 (2000) :Vlangos, C.N., et al. Cytogenet. Cell Genet. 88 (3-4), 283-285 (2000) :Liang, Y., et al. Genomics 61(3):243-258(1999)

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$ 277.78
Cat# BP19144c
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