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XK Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P51811 |
|---|---|
| Clone Names | 100623226 |
| Gene ID | 7504 |
|---|---|
| Other Names | Membrane transport protein XK, Kell complex 37 kDa component, Kx antigen, XK-related protein 1, XK, XKR1, XRG1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | XK {ECO:0000303|PubMed:8004674, ECO:0000312|HGNC:HGNC:12811} |
|---|---|
| Function | Recruits the lipid transfer protein VPS13A from lipid droplets to the endoplasmic reticulum (ER) membrane. |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | High levels in skeletal muscle, heart, brain, and pancreas; low levels in placenta, lung, liver, and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
This locus controls the synthesis of the Kell blood group'precursor substance' (Kx). Mutations in this gene have beenassociated with McLeod syndrome, an X-linked, recessive disordercharacterized by abnormalities in the neuromuscular andhematopoietic systems. The encoded protein has structuralcharacteristics of prokaryotic and eukaryotic membrane transportproteins.
References
Miranda, M., et al. Mov. Disord. 22(9):1358-1361(2007)Claperon, A., et al. Brain Res. 1147, 12-24 (2007) :Walker, R.H., et al. Transfusion 47(2):299-305(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Jung, H.H., et al. Transfusion 43(7):928-938(2003)
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