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VPREB1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P12018
Clone Names 110901249
Additional Information
Gene ID 7441
Other Names Immunoglobulin iota chain, CD179 antigen-like family member A, Protein VPreB1, V(pre)B protein, VpreB protein, CD179a, VPREB1, VPREB
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name VPREB1
Synonyms VPREB
Function Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B- cell differentiation.
Cellular Location Endoplasmic reticulum {ECO:0000250|UniProtKB:P13372}
Tissue Location Only expressed by pre-B-cells.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene belongs to theimmunoglobulin superfamily and is expressed selectively at theearly stages of B cell development, namely, in proB and early preBcells. This gene encodes the iota polypeptide chain that isassociated with the Ig-mu chain to form a molecular complex whichis expressed on the surface of pre-B cells. The complex is thoughtto regulate Ig gene rearrangements in the early steps of B-celldifferentiation.

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Rossi, B., et al. J. Immunol. 177(2):796-803(2006)Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :Gauthier, L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(20):13014-13019(2002)

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$ 277.78
Cat# BP19300c
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