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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PASD1 Antibody (Center) Blocking Peptide   

PASD1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8IV76
Clone Names 90625162
Additional Information
Gene ID 139135
Other Names PAS domain-containing protein 1, Cancer/testis antigen 63, CT63, OX-TES-1, PASD1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PASD1 (HGNC:20686)
Function Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body (PubMed:25936801). Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components (PubMed:25936801). Inhibits circadian clock function in cancer cells, when overexpressed (PubMed:25936801).
Cellular Location [Isoform 1]: Nucleus. Note=Associates preferentially at the periphery of the nucleus with heterochromatin (PubMed:25936801)
Tissue Location Testis-specific (PubMed:25936801). Expressed in a broad range of cancer cells, including melanoma, lung cancer, and breast cancer (at protein level). Testis-specific (PubMed:15162151) Found in histologically normal tissues from patients with uterus, lung and small intestine cancers. Widespread expression seen in solid tumors and diffuse large B-cell lymphoma (DLBCL)-derived cell lines. Isoform 2 is expressed in all DLBCL-derived cell lines, while isoform 1 is preferentially expressed in cell lines derived from non-germinal center DLBCL (PubMed:15162151).
Research Areas
Citations (0)

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This gene encodes a protein that is thought to function asa transcription factor. The protein is a cancer-associated antigenthat can stimulate autologous T-cell responses, and it is thereforeconsidered to be a potential immunotherapeutic target for thetreatment of various hematopoietic malignancies, including diffuselarge B-cell lymphoma.


Ghafouri-Fard, S., et al. Br. J. Dermatol. 162(4):772-779(2010)Ait-Tahar, K., et al. Br. J. Haematol. 146(4):396-407(2009)Sahota, S.S., et al. Blood 108(12):3953-3955(2006)Cooper, C.D., et al. Leukemia 20(12):2172-2174(2006)Guinn, B.A., et al. Biochem. Biophys. Res. Commun. 335(4):1293-1304(2005)

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$ 277.78
Cat# BP19356c
Availability: 2 weeks
Bulk Size

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