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TEKT3 Antibody(N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BXF9
Clone Names 110726246
Additional Information
Gene ID 64518
Other Names Tektin-3, TEKT3
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TEKT3
Function May be a structural component of the sperm flagellum. Required for normal sperm mobility.
Cellular Location Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:A6H782, ECO:0000250|UniProtKB:Q4V8G8} Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane {ECO:0000250|UniProtKB:A6H782, ECO:0000250|UniProtKB:Q4V8G8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q4V8G8}. Note=In the sperm flagellum, localizes to the periaxonemal region where it associates with the mitochondrial sheath and outer dense fibers (By similarity). Not detected in the central axonemal region of the flagellum (By similarity). Associates with the acrosome membrane in the equatorial segment of the sperm head (By similarity). Also detected just below the plasma membrane in the post-acrosomal region where it might localize to the postacrosomal dense lamina (By similarity) However, other studies report little or no expression in the postacrosomal region (By similarity). Translocates from the postacrosomal region to the equatorial segment after sperm activation (By similarity). Retained in the postacromal region, but not the equatorial segment, following the acrosome reaction (By similarity) Some studies report strong expression in the anterior cap region (By similarity). However, other studies report little or no expression in the acrosomal cap (By similarity). {ECO:0000250|UniProtKB:A6H782, ECO:0000250|UniProtKB:Q4V8G8}
Research Areas
Citations (0)

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Background

This gene product belongs to the tektin family ofproteins. Tektins comprise a family of filament-forming proteinsthat are coassembled with tubulins to form ciliary and flagellarmicrotubules. The exact function of this gene is not known.

References

Wilk, J.B., et al. BMC Med. Genet. 8 SUPPL 1, S8 (2007) :Roy, A., et al. Mol. Reprod. Dev. 67(3):295-302(2004)Inoue, K., et al. Genome Res. 11(6):1018-1033(2001)

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$ 277.78
Cat# BP19474a
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