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EPS8L2 Antibody(N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9H6S3
Clone Names 100603135
Additional Information
Gene ID 64787
Other Names Epidermal growth factor receptor kinase substrate 8-like protein 2, EPS8-like protein 2, Epidermal growth factor receptor pathway substrate 8-related protein 2, EPS8-related protein 2, EPS8L2, EPS8R2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EPS8L2
Synonyms EPS8R2
Function Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells (By similarity).
Cellular Location Cytoplasm. Cell projection, stereocilium {ECO:0000250|UniProtKB:Q99K30}. Note=Localizes at the tips of the stereocilia of the inner and outer hair cells {ECO:0000250|UniProtKB:Q99K30}
Tissue Location Detected in fibroblasts and placenta.
Research Areas
Citations (0)

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Background

This gene encodes a member of the EPS8 gene family. Theencoded protein, like other members of the family, is thought tolink growth factor stimulation to actin organization, generatingfunctional redundancy in the pathways that regulate actincytoskeletal remodeling.

References

Kim, J.E., et al. J. Proteome Res. 4(4):1339-1346(2005)Offenhauser, N., et al. Mol. Biol. Cell 15(1):91-98(2004)Tocchetti, A., et al. Genomics 81(2):234-244(2003)

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$ 277.78
Cat# BP19537a
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