NRXN1 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P58400 |
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Gene ID | 9378 |
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Other Names | Neurexin-1-beta, Neurexin I-beta, NRXN1 |
Target/Specificity | The synthetic peptide sequence is selected from aa 77-90 of HUMAN NRXN1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NRXN1 (HGNC:8008) |
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Function | Neuronal cell surface protein involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. Plays a role in formation of synaptic junctions. |
Cellular Location | Presynaptic cell membrane {ECO:0000250|UniProtKB:Q63373}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q63373} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity).
References
Kleiderlein J.J.,et al.Hum. Genet. 103:666-673(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Chen X.,et al.Nat. Struct. Mol. Biol. 15:50-56(2008).
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