|Other Names||YY1-associated protein 1, Hepatocellular carcinoma susceptibility protein, Hepatocellular carcinoma-associated protein 2, YY1AP1, HCCA2, YY1AP|
|Target/Specificity||The synthetic peptide sequence is selected from aa 138-148 of HUMAN YY1AP1|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication (PubMed:27939641). Enhances transcription activation by YY1 (PubMed:14744866). Plays a role in cell cycle regulation (PubMed:17541814, PubMed:27939641).|
|Cellular Location||Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus|
|Tissue Location||Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Enhances transcription activation by YY1. May play a role in cell cycle regulation.
Wang Z.-X.,et al.Br. J. Cancer Suppl. 85:1162-1167(2001).
Wang C.-Y.,et al.J. Biol. Chem. 279:17750-17755(2004).
Zeng J.Z.,et al.Oncogene 21:4932-4943(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
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