PPP6R1 Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UPN7 |
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Gene ID | 22870 |
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Other Names | Serine/threonine-protein phosphatase 6 regulatory subunit 1, SAPS domain family member 1, PPP6R1, KIAA1115, PP6R1, SAPS1 |
Target/Specificity | The synthetic peptide sequence is selected from aa 455-469 of HUMAN PPP6R1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PPP6R1 |
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Synonyms | KIAA1115, PP6R1, SAPS1 |
Function | Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. |
Cellular Location | Cytoplasm |
Tissue Location | Ubiquitous with higher expression in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.
References
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Ohara O.,et al.Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
Olsen J.V.,et al.Cell 127:635-648(2006).
Stefansson B.,et al.J. Biol. Chem. 281:22624-22634(2006).
Stefansson B.,et al.Biochemistry 47:1442-1451(2008).
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