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ADRB3 Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P13945 |
|---|
| Gene ID | 155 |
|---|---|
| Other Names | Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor, ADRB3, ADRB3R, B3AR |
| Target/Specificity | The synthetic peptide sequence is selected from aa 275-289 of HUMAN ADRB3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ADRB3 |
|---|---|
| Synonyms | ADRB3R, B3AR |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Expressed mainly in adipose tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
References
Emorine L.J.,et al.Science 245:1118-1121(1989).
van Spronsen A.,et al.Eur. J. Biochem. 213:1117-1124(1993).
Lelias J.M.,et al.FEBS Lett. 324:127-130(1993).
Kopatz S.A.,et al.Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Granneman J.G.,et al.Mol. Pharmacol. 42:964-970(1992).
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