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NUP93 Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N1F7 |
|---|---|
| Other Accession | Q5R822 |
| Gene ID | 9688 |
|---|---|
| Other Names | Nuclear pore complex protein Nup93, 93 kDa nucleoporin, Nucleoporin Nup93, NUP93, KIAA0095 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 772-782 of HUMAN NUP93 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NUP93 |
|---|---|
| Synonyms | KIAA0095 |
| Function | Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:9348540). May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (PubMed:26878725). |
| Cellular Location | Nucleus membrane {ECO:0000250|UniProtKB:Q66HC5}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q66HC5}. Nucleus, nuclear pore complex. Nucleus envelope Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC.
References
Nagase T.,et al.DNA Res. 2:37-43(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Grandi P.,et al.Mol. Biol. Cell 8:2017-2038(1997).
Hase M.E.,et al.Mol. Biol. Cell 14:1923-1940(2003).
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