|Other Names||Neuroendocrine convertase 1, NEC 1, 184.108.40.206, Prohormone convertase 1, Proprotein convertase 1, PC1, PCSK1, NEC1|
|Target/Specificity||The synthetic peptide sequence is selected from aa 702-715 of HUMAN PCSK1|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.
Creemers J.W.M.,et al.FEBS Lett. 300:82-88(1992).
Seidah N.G.,et al.DNA Cell Biol. 11:283-289(1992).
Ohagi S.,et al.Diabetes 45:897-901(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
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