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Phospho-CCNB2(T359) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O95067
Other Accession NP_004692.1
Additional Information
Gene ID 9133
Other Names G2/mitotic-specific cyclin-B2, CCNB2
Target/Specificity The synthetic peptide sequence is selected from aa 353-366 of HUMAN CCNB2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCNB2
Function Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Research Areas
Citations (0)
citation

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Background

Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.

References

Cunningham, J.M., et al. Br. J. Cancer 101(8):1461-1468(2009)
Haraguchi, T., et al. Fertil. Steril. 91 (4 SUPPL), 1424-1426 (2009) :
De Martino, I., et al. Cancer Res. 69(5):1844-1850(2009)
Bellanger, S., et al. Oncogene 26(51):7175-7184(2007)
Stav, D., et al. Int. J. Biol. Markers 22(2):108-113(2007)

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$ 277.78
Cat# BP3840a
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Availability: 2 weeks
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