|Other Names||G2/mitotic-specific cyclin-B2, CCNB2|
|Target/Specificity||The synthetic peptide sequence is selected from aa 353-366 of HUMAN CCNB2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Essential for the control of the cell cycle at the G2/M (mitosis) transition.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
Cunningham, J.M., et al. Br. J. Cancer 101(8):1461-1468(2009)
Haraguchi, T., et al. Fertil. Steril. 91 (4 SUPPL), 1424-1426 (2009) :
De Martino, I., et al. Cancer Res. 69(5):1844-1850(2009)
Bellanger, S., et al. Oncogene 26(51):7175-7184(2007)
Stav, D., et al. Int. J. Biol. Markers 22(2):108-113(2007)
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